I have an old friend who happens to be an honest-to-God '60s British rock star (whose fame has sadly faded, but the man can still play, mainly rockabilly, but I digress) - he related a story to me once:

He was a member of someone famous' band (I forget who, let's say Clapton just for the purpose of the story) around 1970, and some kid, an up-and-coming talent and a huge fan, asked if he could play Clapton's guitar once. He picked up the guitar and took a strum and it sounded like sh*t.

Same guitar, same rig, but different technique. Clapton's (or Gilmour's) guitar sounds like that mostly because it's Eric or Dave playing it.

The point is, get some experience, listen, and experiment. Read "The Black Strat" (http://www.theblackstrat.com) written by Dave's guitar tech... and most of all, PRACTICE. Use Dave as an inspiration, certainly, but develop your own tone.

Good luck!