In the movie, Jack Black dreams of his band singing this song when they get the Pick Of Destiny that's supposed to make them unbelievable rock stars. The song was intentionally made to be impossible to play. Tenacious D never sang it, they lip synced it live, and they consider it as a sort of a comedy show. So, is this song impossible to play?

http://www.youtube.com/watch?v=7I0R_ktQj-k

Nope nothings impossible, if they can make the track then they can play it.

Yeah, but they buffed it with effects...the vocals seem pretty hard to me.

not really just alot of delay and overdubs.
could be done live with a protools desk but i get what you mean. not impossible but a bit tricky.

The guitar part looks harder than it actually is, if you see kyle playing the 2 neck guitar solo its actually one guitar with an octaver.